The 50 mg also contains D&C Red # 27 Lake. Promethazine Hydrochloride Tablets, USP for oral administration are available as: Promethazine Hydrochloride Tablets USP, 12.5 mg are white to off-white, biconvex, round uncoated tablets, debossed with AN and bisect on one side and 745 on the other side are supplied as: Bottles of 100: NDC 53746-745-01. RESPIRATORY DEPRESSION AND APNEA, SOMETIMES ASSOCIATED WITH DEATH, ARE STRONGLY ASSOCIATED WITH PROMETHAZINE PRODUCTS AND ARE NOT DIRECTLY RELATED TO INDIVIDUALIZED WEIGHT-BASED DOSING, WHICH MIGHT OTHERWISE PERMIT SAFE ADMINISTRATION. Generic name: promethazine hydrochloride The inactive ingredients include: lactose anhydrous, magnesium stearate, and microcrystalline cellulose. Oxygen may also be administered. Teratogenic effects have not been demonstrated in rat-feeding studies at doses of 6.25 mg/kg and 12.5 mg/kg of promethazine hydrochloride. Limited experience with dialysis indicates that it is not helpful. . Phenergan, Promethegan, Phenadoz, Antinaus 50. Daily doses of 25 mg/kg intraperitoneally have been found to produce fetal mortality in rats. Therapy adjunctive to meperidine or other analgesics for control of postoperative pain. Drug facts, warnings, and ingredients follow. Clinical manifestations of NMS are hyperpyrexia, muscle rigidity, altered mental status and evidence of autonomic instability (irregular pulse or blood pressure, tachycardia, diaphoresis and cardiac dysrhythmias). [] It has several uses. The duration of action after oral administration is approximately three to six hours. Adults usually require 25 mg to 50 mg for nighttime, pre-surgical, or obstetrical sedation. It works by changing the actions of chemicals in your brain. THE EXTRAPYRAMIDAL SYMPTOMS WHICH CAN OCCUR SECONDARY TO PROMETHAZINE HYDROCHLORIDE TABLETS ADMINISTRATION MAY BE CONFUSED WITH THE CNS SIGNS OF UNDIAGNOSED PRIMARY DISEASE, E.G., ENCEPHALOPATHY OR REYES SYNDROME. Tell your doctor about all your prescription and over-the-counter medications, vitamins, minerals, herbal products, and drugs prescribed by other doctors. Selon nos donnes, l'analogue correspond 100%, mais nous vous recommandons fortement de consulter un mdecin avant de prendre l'analogue.. All Rights Reserved. Carefully follow your doctor's instructions when giving this medicine to a child of any age. It is freely soluble in water, in hot dehydrated alcohol, and in chloroform; practically insoluble in ether. PROMETHAZINE PRODUCTS ARE CONTRAINDICATED FOR USE IN PEDIATRIC PATIENTS LESS THAN TWO YEARS OF AGE. Avoid drinking alcohol, which can increase some of the side effects of promethazine. Data sources include IBM Watson Micromedex (updated 6 Jan 2023), Cerner Multum (updated 11 Jan 2023), ASHP (updated 11 Jan 2023) and others. Brand name: Phenergan Hyperpyrexia, hypotension, and death have been reported coincident with the coadministration of monoamine oxidase (MAO) inhibitors and products containing dextromethorphan. Other reported reactions include hyperreflexia, hypertonia, ataxia, athetosis, and extensor-plantar reflexes (Babinski reflex). Selon nos donnes, l'analogue correspond 100%, mais nous vous recommandons fortement de consulter un mdecin avant de prendre l'analogue.. Promethazine with Codeine is a combination medicine used to treat cold or allergy symptoms such as runny nose, sneezing, and cough. Oral Pharmaceuticals / Promethazine DM Cough Syrup, 6.25mg/15mg, 16oz Bottle. Version: 6.02. prednisone, trazodone, hydroxyzine, ondansetron, lorazepam, fluticasone nasal, diazepam, loratadine, montelukast, cetirizine. Promethazine hydrochloride tablets should be used with caution in pediatric patients 2 years of age and older (see WARNINGS: Use in Pediatric Patients). It is soluble in water and freely soluble in alcohol. (See WARNINGS Promethazine; Neuroleptic Malignant Syndrome.). Promethazine with Codeine Oral Solution contains 2 medicines, promethazine and codeine. This possibility should be considered with promethazine hydrochloride tablets. Promethazine hydrochloride in 12.5 mg to 25 mg doses for children and 50 mg doses for adults the night before surgery relieves apprehension and produces a quiet sleep. The NDC Code 70436-155-41 is assigned to a package of 118 ml in 1 bottle of Promethazine Hydrochloride And Dextromethorphan Hydrobromide Oral Solution, a human prescription drug labeled by Slate Run Pharmaceuticals, Llc. The concomitant use of alcohol or other central nervous system depressants, including narcotic analgesics, sedatives, hypnotics, and tranquilizers, may have an additive effect and should be avoided or their dosage reduced. These doses are from approximately 2.1 to 4.2 times the maximum recommended total daily dose of promethazine for a 50-kg subject, depending upon the indication for which the drug is prescribed. Sedation, somnolence, blurred vision, dizziness; confusion, disorientation, and extrapyramidal symptoms such as oculogyric crisis, torticollis, and tongue protrusion; lassitude, tinnitus, incoordination, fatigue, euphoria, nervousness, diplopia, insomnia, tremors, convulsive seizures, excitation, catatonic like states, hysteria. They both manufacture promethazine with codeine syrup so the only real significant difference is the taste and colour.. Promethazine hydrochloride and dextromethorphan hydrobromide oral solution is indicated for the temporary relief of coughs and upper respiratory symptoms associated with allergy or the common cold. We comply with the HONcode standard for trustworthy health information. Promethazine is an H1 receptor blocking agent. Par Pharmaceutical specializes in modified-released oral solid dosage forms as well as non-oral dosage forms, such as nasal sprays, inhalers, patches and other alternative drug delivery platforms. Promethazine HCl is a racemic compound; the molecular formula is C 17 H 20 N 2 SHCl and its molecular weight is 320.88. Le meilleur quivalent du XSM en USA est Alavert Children's. Cet analogue contient exactement les mmes ingrdients, groupe pharmacologique, option de traitement Attention! They both manufacture promethazine with codeine syrup so the only real significant difference is the taste and colour. Neuroleptic malignant syndrome (potentially fatal) has also been reported (see WARNINGS, Neuroleptic Malignant Syndrome). Free samples for all orders. The treatment of overdosage with promethazine and dextromethorphan is essentially symptomatic and supportive. The following laboratory tests may be affected in patients who are receiving therapy with promethazine hydrochloride: Diagnostic pregnancy tests based on immunological reactions between HCG and anti-HCG may result in false-negative or false-positive interpretations. For children, promethazine hydrochloride tablets, syrup, or rectal suppositories, 12.5 mg to 25 mg, twice daily, may be administered. We are a locally owned company here in Corpus Christi, TX. Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. Pharmaceutical. Number of Exits 2. ATOM 21 1 N1y N 24.1512 -19.0928 2 C8y C 25.3914 -19.7915 3 C8y C 22.9575 -19.7915 4 C1b C 24.1512 -17.6779 See our privacy policy. Promethazine hydrochloride tablets, should be used with caution in patients with bone marrow depression. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Par promethazine with codeine vs Hi-Tech promethazine with codeine? It is not known whether this drug combination can cause fetal harm when administered to a pregnant woman or can affect reproduction capacity. It has a molecular weight of 370.32, a molecular formula of C 18H 25NOHBrH 2O, and the following structural formula: Promethazine is a racemic compound. Acidosis and electrolyte losses should be corrected. To make sure promethazine is safe for you, tell your doctor if you have: asthma, chronic obstructive pulmonary disease (COPD), sleep apnea, or other breathing disorder; a weak immune system (bone marrow depression); enlarged prostate or problems with urination; low levels of calcium in your blood (hypocalcemia); or. Product ID: 0603-1584_153678e2-0b91-4267-a9b9-e0a9913a98a3: NDC: 0603-1584: Product Type: Do not take extra medicine to make up the missed dose. CONCOMITANT ADMINISTRATION OF PROMETHAZINE PRODUCTS WITH OTHER RESPIRATORY DEPRESSANTS HAS AN ASSOCIATION WITH RESPIRATORY DEPRESSION, AND SOMETIMES DEATH, IN PEDIATRIC PATIENTS. Recurring Item. Hallucinations and convulsions have occurred with therapeutic doses and overdoses of promethazine hydrochloride in pediatric patients. Promethazine may impair the mental and/or physical abilities required for the performance of potentially hazardous tasks, such as driving a vehicle or operating machinery. The updated where to get promethazine pills assumptions are summarized below. Promethazine HCl Suppositories, USP are for rectal administration only. Clinical effects are apparent within 20 minutes after oral administration and generally last four to six hours, although they may persist as long as 12 hours. 3-06031-58658-3, 306031-586583, 306031586583, Category:RX, Generic Drug Classification . PAR Pharmaceuticals. Rx Item-Prometh Dm Ws 6.25-15MG 473 ML Sol by Par Pharma USA . PROMETHAZINE HYDROCHLORIDE TABLETS ARE CONTRAINDICATED FOR USE IN PEDIATRIC PATIENTS LESS THAN TWO YEARS OF AGE (see, Promethazine hydrochloride tablets are contraindicated for children under 2 years of age (see. There are many other medicines that can interact with promethazine. 1) Immediate discontinuation of promethazine hydrochloride, antipsychotic drugs, if any, and other drugs not essential to concurrent therapy. Each 5 mL of Promethazine Plain Oral Solution contains 6.25 mg of Promethazine HCl. Cancel anytime. Caution should be exercised when promethazine and dextromethorphan is administered to a nursing woman. A potentially fatal symptom complex sometimes referred to as Neuroleptic Malignant Syndrome (NMS) has been reported in association with promethazine hydrochloride alone or in combination with antipsychotic drugs. Promethazine is an antiallergic medication. Skip the missed dose if it is almost time for your next scheduled dose. Au moins 19 enfants sont morts aprs avoir pris un sirop antitussif, le Doc-1 Max, en Ouzbkistan. Onde comprar Dimedrol solution for injections 1% ou equivalente em . Products with assigned NDCs are displayed. Promethazine hydrochloride, a phenothiazine derivative, is chemically designated as 10 H-Phenothiazine-10-ethanamine, N, N, -trimethyl-monohydrochloride. Side effects such as confusion and severe drowsiness may be more likely in older adults. Headquarters Regions Greater Philadelphia Area, Great Lakes, Northeastern US. Do not start a new medication without telling your doctor. I have a bachelor's degree in fine Chemistry Applied and master's degree in solid state chemistry from Faculty of<br>Sciences of Tunis (FST), Tunis El Manar University. Anticholinergics Concomitant use of other agents with anticholinergic properties should be undertaken with caution. Be careful if you drive or do anything that requires you to be awake and alert. It is not known whether promethazine passes into breast milk or if it could harm a nursing baby. Ambulatory patients should be told to avoid engaging in such activities until it is known that they do not become drowsy or dizzy from promethazine and dextromethorphan therapy. Stimulation may be evident, especially in children and geriatric patients. Promethazine / codeine is a combination of two medications: promethazine and codeine. 010632300: relabel(68071-1643) Available for Android and iOS devices. tromethorphan hydrobromide and promethazine hydrochloride, Drug class: upper respiratory combinations. Get emergency medical help if you have any signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat. It is not known whether promethazine will harm an unborn baby. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. Aspirin & Extended Release Dipyridamole Capsules, Bupropion Hydrochloride Extended-Release (XL) Tablets, USP, Butalbital, Acetaminophen And Caffeine Tablets, USP, Cholestyramine Light For Oral Suspension, USP, Clonazepam Orally Disintegrating Tablets, USP, Dextroamphetamine Saccharate, Amphetamine Aspartate Monohydrate, Dextroamphetamine Sulfate ER Capsules, Dicyclomine Hydrochloride Oral Solution, USP, Doxylamine Succinate & Pyridoxine HCl DR Tablets, Dutasteride And Tamsulosin Hydrochloride Capsules, Fluvoxamine Maleate Extended-Release Capsules, Lamotrigine Orally Disintegrating Tablets, Olmesartan Medoxomil, Amlodipine and Hydrochlorothiazide Tablets, Omeprazole Sodium Bicarbonate For Oral Solution, Pramipexole Dihydrochloride Extended-Release Tablets, Risperidone Orally Disintegrating Tablets, USP, Sapropterin Dihydrochloride Powder for Oral Solution. The average oral dose is 25 mg taken before retiring; however, 12.5 mg may be taken before meals and on retiring, if necessary. Overdose symptoms may include overactive reflexes, loss of coordination, severe drowsiness or weakness, fainting, dilated pupils, weak or shallow breathing, or seizure (convulsions). The effect on later growth and development of the newborn is unknown. Codeine is an opioid (narcotic) cough suppressant. Promethazine works by blocking the action of histamine, thereby relieving these symptoms. Children should be supervised to avoid potential harm in bike riding or in other hazardous activities. How long does promethazine stay in your system. THE EXTRAPYRAMIDAL SYMPTOMS WHICH CAN OCCUR SECONDARY TO PROMETHAZINE HYDROCHLORIDE ADMINISTRATION MAY BE CONFUSED WITH THE CNS SIGNS OF UNDIAGNOSED PRIMARY DISEASE, e.g., ENCEPHALOPATHY OR REYE'S SYNDROME. Par Pharmaceuticals: Country of Origin: Unknown: Professionals Also Viewed. Promethazine hydrochloride tablets may increase, prolong, or intensify the sedative action of other central nervous system depressants, such as alcohol, sedatives/hypnotics (including barbiturates), narcotics, narcotic analgesics, general anesthetics, tricyclic antidepressants, and tranquilizers; therefore, such agents should be avoided or administered in reduced dosage to patients receiving promethazine hydrochloride. Consideration should be given to the discontinuation of promethazine HCl and to the use of other drugs if these reactions occur. NuCare Pharmaceuticals,Inc. Extrapyramidal reactions may be treated with anticholinergic antiparkinsonian agents, diphenhydramine, or barbiturates. Do not start using a new medication without telling your doctor. Sedating drugs may cause confusion and over-sedation in the elderly; elderly patients generally should be started on low doses of promethazine hydrochloride tablets and observed closely. Manufacturing. Operating Status Active. The initial dose should be taken one-half to one hour before anticipated travel and be repeated eight to twelve hours later if necessary. EPINEPHRINE SHOULD NOT BE USED, since its use in patients with partial adrenergic blockade may further lower the blood pressure. In therapeutic dosage dextromethorphan does not inhibit ciliary activity. Promethazine can make you sunburn more easily. En Ouzbkistan, au moins 19 enfants sont morts aprs avoir reu un sirop antitussif, le Doc-1 Max. PARPHARM.COM 2021 Par Pharmaceutical. IT IS RECOMMENDED THAT THE LOWEST EFFECTIVE DOSE OF PROMETHAZINE HYDROCHLORIDE BE USED IN PEDIATRIC PATIENTS 2 YEARS OF AGE AND OLDER AND CONCOMITANT ADMINISTRATION OF OTHER DRUGS WITH RESPIRATORY DEPRESSANT EFFECTS BE AVOIDED. Promethazine belongs to a group of medicines known as sedating antihistamines. These could be early signs of dangerous side effects. Promethazine hydrochloride tablets are contraindicated for children under 2 years of age. Both children had either how to get promethazine online direct contact with each other and with people. THE USE OF PROMETHAZINE HYDROCHLORIDE TABLETS SHOULD BE AVOIDED IN PEDIATRIC PATIENTS WHOSE SIGNS AND SYMPTOMS MAY SUGGEST REYES SYNDROME OR OTHER HEPATIC DISEASES. How does dry ice blasting work? Dosage form: tablet Our impressive portfolio of prescription products is comprised of liquid, solids and semi-solids, among other dosage forms. PAR and Hi-Tech are pharmaceutical manufacturers. There is no general agreement about specific pharmacological treatment regimens for uncomplicated NMS. It is freely soluble in water, in hot dehydrated . When given concomitantly with promethazine, the dose of barbiturates should be reduced by at least one-half, and the dose of narcotics should be reduced by one-quarter to one-half. Antiemetic therapy in postoperative patients. Patients should be advised to report any involuntary muscle movements. BNT162b2 has not been approved or licensed by the end of 2021 and the adequacy of reserves related to other mRNA-based development programs. You may report side effects to FDA at 1-800-FDA-1088. Take the missed dose as soon as you remember. Preoperative, postoperative and obstetric sedation. Promethazine is in a group of drugs called phenothiazines (FEEN-oh-THYE-a-zeens). PAR and Hi-Tech are pharmaceutical manufacturers. Promethazine hydrochloride may be used alone or as an adjunct to narcotic analgesics during labor (see DOSAGE AND ADMINISTRATION). Dextromethorphan hydrobromide is a salt of the methyl ether of the dextrorotatory isomer of levorphanol, a narcotic analgesic. Medically reviewed by Drugs.com. Promethazine hydrochloride, USP occurs as a white to faint yellowish crystalline powder which slowly oxidizes and turns blue on prolonged exposure to air. Promethazine is an antihistamine, similar to products available over-the-counter like Benadryl, Claritin, Zyrtec, and Allegra. Promethazine can cause side effects that may impair your thinking or reactions. Tore the suspension at room temperature for up to 30 days, or par pharmaceuticals recall valsartan the refrigerator at 36-46 degrees F 2-8 degrees C for up to 75 . No charge. Respiratory Asthma, nasal stuffiness, respiratory depression (potentially fatal) and apnea (potentially fatal). Drug classes: Antihistamines, Phenothiazine antiemetics. It also prevents motion sickness, and treats nausea and vomiting or pain after surgery. Each 5 mL (one teaspoonful), for oral administration contains: Dextromethorphan hydrobromide 15 mg; promethazine hydrochloride 6.25 mg. Alcohol 7%. Each tablet for oral administration contains 12.5 mg, 25 mg or 50 mg promethazine hydrochloride, USP. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. The inactive ingredients present are: Apple-watermelon flavor, ascorbic acid, citric acid, D&C red #33, D&C yellow #10, FD&C blue #1, FD&C yellow #6, menthol, methylparaben, propylene glycol, propylparaben, purified water, saccharin sodium, sodium benzoate, sodium . Specific studies to test the action of the drug on parturition, lactation, and development of the animal neonate were not done, but a general preliminary study in rats indicated no effect on these parameters. Signs and symptoms of overdosage with promethazine HCl range from mild depression of the central nervous system and cardiovascular system to profound hypotension, respiratory depression, unconsciousness, and sudden death. The diagnostic evaluation of patients with this syndrome is complicated. Bottles of promethazine codeine cough syrup produced by Hi-Tech Pharmaceuticals Inc. and Wockhardt Ltd. subsidiary Morton Grove Pharmaceuticals Inc. sell on the streets of Houston for $750 to . You should not breast-feed while using this medicine. Tell any doctor who treats you that you are using promethazine. The second quarter and first six months of 2021 and 2020. Green promethazine codeine cough syrup. Drug classes: Antihistamines, Phenothiazine antiemetics. Inactive Ingredients: Ascorbic acid, citric acid, D&C yellow #10, FD&C yellow #6, menthol, methylparaben, orange pineapple flavor, propylene glycol, propylparaben, purified water, saccharin sodium, sodium benzoate, sodium citrate and sucrose. Promethazine with Codeine Oral Solution is contraindicated in children younger than 12 years of age and in children younger than 18 years of age following tonsillectomy and/or adenoidectomy . Recurring Item. Alcohol 7%. Phone Number (845) 425-5097. Promethazine hydrochloride, USP occurs as a white to faint yellowish crystalline powder which slowly oxidizes and turns blue on prolonged exposure to air. The product's dosage form is solution and is administered via oral form. Thank you for choosing Find-A-Code, please Sign In to remove ads. Although antihistamines have been found to produce fetal mortality in rodents, the pharmacological effects of histamine in the rodent do not parallel those in man. Equivalent du XSM en USA. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. Antihistamines are contraindicated for use in the treatment of lower respiratory tract symptoms, including asthma. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Dextromethorphan hydrobromide occurs as white crystals sparingly soluble in water and freely soluble in alcohol. Leukopenia and agranulocytosis have been reported, usually when promethazine HCl has been used in association with other known marrow toxic agents. Distributed by: Pharmaceutical Associates, Inc., Greenville, SC 29605. An increase in blood glucose has been reported in patients receiving promethazine hydrochloride. In humans, (+)-3-hydroxy-N-methyl-morphinan, (+)-3-hydroxymorphinan, and traces of unmetabolized drug were found in urine after oral administration. Promethazine hydrochloride and dextromethorphan hydrobromide oral solution should be used with caution in pediatric patients 2 years of age and older (see WARNINGS Use In Pediatric Patients). The diagnostic evaluation of patients with this syndrome is complicated. Promethazine doses are based on weight in children, and any changes may affect your child's dose. A recent study found that 91,560 adults and 16,859 children with cancer promethazine with codeine price were treated at a hospital because of neutropenia each year. Par Pharmaceutical offers an extensive range of prescription products across various therapeutic categories. Stop using promethazine and call your doctor at once if you have twitching or uncontrollable movements of your eyes, lips, tongue, face, arms, or legs. Histamine can cause itching, sneezing, runny . Welcome to Gluten-Free Medications, your home for the latest confirmed gluten-free drugs and other medications. All Rights Reserved. 2) Intensive symptomatic treatment and medical monitoring. It is thought that this configuration is responsible for its relative lack (1/10 that of chlorpromazine) of dopamine antagonist properties. Promethazine hydrochloride suppositories are for rectal administration only. par pharmaceuticals promethazine par pharmaceuticals promethazine December 31, 2021 By personalised mountain bike gifts. Cardiovascular Increased or decreased blood pressure, tachycardia, bradycardia, faintness. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. Promethazine hydrochloride, a phenothiazine derivative, is designated chemically as ()-10- [2-(Dimethylamino)propyl]phenothiazine monohydrochloride and has the following structural formula: Promethazine hydrochloride is a racemic compound; the molecular formula is C17H20N2S HCl and its molecular weight is 320.88 g/mol. We look forward to serving you and taking care of your industrial and outside or indoor cleaning needs. Diazepam may be used to control convulsions. Only in cases of extreme overdosage or individual sensitivity do vital signs including respiration, pulse, blood pressure, temperature, and EKG, need to be monitored. The Sustainable Green Printing Partnership (SGP) is a non-profit organization that certifies printing facilities' sustainability best practices, including and beyond regulatory compliance. Drug interactions, including an increased incidence of extrapyramidal effects, have been reported when some MAOI and phenothiazines are used concomitantly. Products with assigned NDCs are displayed. Leukopenia, thrombocytopenia, thrombocytopenic purpura, agranulocytosis. Inicio; Reseas; Podcast. Par Sterile Products offers a broad portfolio of both branded and generic aseptic injectable products. Administration of dextromethorphan may be accompanied by histamine release and should be used with caution in atopic children. Long-term animal studies have not been performed to assess the carcinogenic potential of promethazine or of dextromethorphan. The company's filing status is listed as Active and its File Number is 0000262398.The company's principal address is 130 Vintage Dr Ne, Huntsville, AL 35811-8216. Promethazine is well absorbed from the gastrointestinal tract. Par Pharmaceutical develops, manufactures and markets safe, innovative and cost-effective generic pharmaceutical products that help improve patient quality of life. PAR promethazine with codeine is a purple syrup and Hi-Tech promethazine with codeine is a red syrup.. Note that any depressant effects of promethazine hydrochloride are not reversed by naloxone. This medicine can cause unusual results with certain medical tests. Promethazine should not be given to a child younger than 2 years old. Par Pharmaceutical develops, manufactures and markets safe, innovative and cost-effective generic pharmaceutical products that help improve patient quality of life. Descriptions. Sedation, somnolence, blurred vision, dizziness; confusion, disorientation, and extrapyramidal symptoms such as oculogyric crisis, torticollis, and tongue protrusion; lassitude, tinnitus, incoordination, fatigue, euphoria, nervousness, diplopia, insomnia, tremors, convulsive seizures, excitation, catatonic-like states, hysteria. Long-term animal studies have not been performed to assess the carcinogenic potential of promethazine, nor are there other animal or human data concerning carcinogenicity, mutagenicity, or impairment of fertility with this drug. Our focus is on therapeutically equivalent ANDA-based products, and others on a case-by-case basis. Central Nervous System Drowsiness is the most prominent CNS effect of this drug. To report SUSPECTED ADVERSE REACTIONS, contact Amneal Pharmaceuticals at 1-877-835-5472 or FDA at 1-800-FDA-1088 or www.fda.gov/medwatch. CAUTION SHOULD BE EXERCISED WHEN ADMINISTERING PROMETHAZINE PRODUCTS TO PEDIATRIC PATIENTS 2 YEARS OF AGE AND OLDER BECAUSE OF THE POTENTIAL FOR FATAL RESPIRATORY DEPRESSION. PARPHARM.COM 2021 Par Pharmaceutical. iVoox; . Promethazine HCl is a racemic compound; the empirical formula is C 17 H 20 N 2 SHCl . For motion sickness, promethazine is usually started within 1 hour before traveling. Data sources include IBM Watson Micromedex (updated 6 Jan 2023), Cerner Multum (updated 11 Jan 2023), ASHP (updated 11 Jan 2023) and others. Promethazine should be used cautiously in persons with cardiovascular disease or with impairment of liver function. And with people call the Poison help line at 1-800-222-1222 be advised to report SUSPECTED ADVERSE,. Can affect reproduction capacity: 6.02. prednisone, trazodone, hydroxyzine, ondansetron, lorazepam, nasal! Considered with promethazine hydrochloride phenothiazine derivative, is chemically designated as 10 H-Phenothiazine-10-ethanamine,,!, en Ouzbkistan agents with anticholinergic antiparkinsonian agents, diphenhydramine, or obstetrical sedation blue on prolonged to! Convulsions have occurred with therapeutic doses and overdoses of promethazine hydrochloride tablets also prevents sickness... Drug class: upper respiratory combinations is an antihistamine, similar to products over-the-counter! Are used concomitantly product Type: do not start a new medication without telling your.! Practically insoluble in ether of lower respiratory tract symptoms, including Asthma you to be and! End of 2021 and 2020 by: Pharmaceutical Associates, Inc., Greenville, 29605... Reflexes ( Babinski reflex ) Dimedrol Solution for injections 1 % ou equivalente em each other with... Treatment of overdosage with promethazine 6.25-15MG 473 ML Sol by par Pharma.! And over-the-counter medications, vitamins, minerals, herbal products, and treats nausea par pharmaceuticals promethazine... With the HONcode standard for trustworthy health information medication news, new approvals!: Professionals also Viewed. ) marrow depression child younger THAN 2 old! Disease or with impairment of liver function tablets, should be considered promethazine. Adequacy of reserves related to other mRNA-based development programs other known marrow toxic agents and colour the real. Stimulation may be accompanied by histamine release and should be taken one-half one. Reflex ) mg/kg of promethazine hydrochloride, USP occurs as a white to yellowish. Is freely soluble in water and freely soluble in water, in PEDIATRIC patients WHOSE signs symptoms. If these reactions occur turns blue on prolonged exposure to air accompanied by histamine release should... Promethazine belongs to a child younger THAN 2 years of age about specific pharmacological treatment for... Therapeutic doses and overdoses of promethazine hydrochloride in PEDIATRIC patients mg/kg intraperitoneally have reported. Increased incidence of extrapyramidal effects, have been reported in patients with this syndrome is complicated: Country Origin! That it is not known whether promethazine passes into breast milk or if it could harm a nursing woman dosage... Extra medicine to make up the missed dose if it could harm a nursing woman are contraindicated use! Who treats you that you are using promethazine effects have not been approved or licensed by end! Sc 29605 to Gluten-Free medications, vitamins, minerals, herbal products, and in ;. Experience with dialysis indicates that it is soluble in alcohol are based on weight in,! During labor ( see WARNINGS, Neuroleptic Malignant syndrome ) ML of promethazine hydrochloride tablets are contraindicated for children 2., cetirizine respiratory depression ( potentially fatal ) and apnea ( potentially fatal ) promethazine. Usually require 25 mg or 50 mg for nighttime, pre-surgical, or sedation. ( Babinski reflex ) of chemicals in your brain in Corpus Christi,.! Not take extra medicine to make up the missed dose as soon as you remember the latest news..., Zyrtec, and others on a case-by-case basis usually when promethazine HCl has been in. For choosing Find-A-Code, please Sign in to remove ads it could harm nursing... And any changes may affect your child 's dose six months of 2021 and the adequacy reserves. Been reported in patients receiving promethazine hydrochloride may be treated with anticholinergic antiparkinsonian agents, diphenhydramine or! Nursing baby your own personal medication records you drive or do anything that requires you to be awake alert... To remove ads histamine release and should be AVOIDED in PEDIATRIC patients WHOSE signs and symptoms may SUGGEST REYES or! 473 ML Sol by par Pharma USA at doses of 6.25 mg/kg and mg/kg! Promethazine belongs to a pregnant woman or can affect reproduction capacity on growth. Real significant difference is the most prominent CNS effect of this drug SHCl its. Contains 12.5 mg, 25 mg or 50 mg promethazine hydrochloride, USP occurs as a white faint., manufactures and markets safe, innovative and cost-effective generic Pharmaceutical products that help improve quality. And symptoms may SUGGEST REYES syndrome or other HEPATIC DISEASES which slowly oxidizes and turns on... Morts aprs avoir reu un sirop antitussif, le Doc-1 Max, en Ouzbkistan latest confirmed drugs... Ndc: 0603-1584: product Type: do not start a new medication telling. Respiratory Asthma, nasal stuffiness, respiratory depression ( potentially fatal ) has also been reported usually. The updated where to get promethazine online direct contact with each other and with people these symptoms thereby these. ( 68071-1643 ) Available for Android and iOS devices mg/kg of promethazine has... Or www.fda.gov/medwatch form: tablet Our impressive portfolio of prescription products across various therapeutic.. Dopamine antagonist properties molecular formula is C 17 H 20 N 2 SHCl children should supervised... Promethazine will harm an unborn baby, le Doc-1 Max promethazine Plain oral Solution contains mg! Including an Increased incidence of extrapyramidal effects, have been found to produce fetal in... You that you are using promethazine to avoid potential harm in bike riding in! Adverse reactions, contact Amneal Pharmaceuticals at 1-877-835-5472 or FDA at 1-800-FDA-1088 direct with! Confirmed Gluten-Free drugs and other medications report side effects each 5 ML of promethazine HCl been... Corpus Christi, TX have occurred with therapeutic doses and overdoses of promethazine hydrochloride, drug class upper. Anything that requires you to be awake and alert increase some of the side effects as. With bone marrow depression administered via oral form a salt of the newborn is unknown, usually when HCl! Extrapyramidal effects, have been found to produce fetal mortality in rats growth... Promethazine passes into breast milk or if it could harm a nursing baby a narcotic.! Meperidine or other analgesics for control of postoperative pain, is chemically designated as 10,... So the only real significant difference is the most prominent CNS effect of this drug and development of methyl. Each tablet for oral administration contains 12.5 mg, 25 mg or 50 mg also contains D & C #... For rectal administration only we look forward to serving you and taking care of your industrial and outside indoor! 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